by Erfani, Sadi
Botox, Dysport And Xeomin
By Sadi Erfani, MD
“What is the difference between Botox, Dysport and Xeomin?” and “Which is the best one?” are two questions about facial injectables that commonly get asked. Botox is a leading cosmetic treatment that drastically reduces the appearance of crow’s feet, lines on the forehead and frown lines. With US FDA approval and launch of this revolutionary anti-aging product in 1989, millions continue to turn to Botox over 20 years later as part of their aesthetic regimen for looking younger. However, two other companies have entered the market as well and are having great success as well, Dysport (US FDA approved 2009) and Xeomin (US FDA approved 2011).
Botox, Dysport and Xeomin Similarities
It is understandable how one would want to know about Botox, Dysport and Xeomin when trying to determine which treatment is best for them. All three are effective treatments that originate from the same source bacterium, clostridium botulinum. They are synthesized as botulinum toxin type A, the paralyzing agent or neurotoxin that is administered. Each has been consistently proven in clinical trials and then worldwide application. The result is almost always the same. Each injectable temporarily paralyzes the targeted muscle areas on the face to relax and ease out the appearance of wrinkles. Because of their proven abilities, each is often paired with a dermal filler like Restylane or Juvederm that results in dramatic facial rejuvenation. This procedure is known as a liquid facelift. However, what follows is where the differences become apparent.
Differences Of Botox, Dysport and Xeomin
Xeomin is a purified neurotoxin. It is referred to as a ‘naked’ molecule because there are no additive surface proteins, just the botulinum toxin. This solitary agent migrates further and faster to effectively work upon all facial areas upon injection. There is less risk of an allergic reaction or rejection for the client from the absence of protein additives. In comparison, Botox and Dysport are considered ‘heavier’ because they contain added proteins. These proteins are for protection and are clustered around the botulinum to enable them to last a little longer. However, the clinical argument is that these protective proteins may also shield the active part of the neurotoxin thereby minimizing product effectiveness.
One of the noted benefits of Dysport is that it spreads a little more than Botox and it is commonly used by patients who have stopped responding to Botox. It is also injected at a different strength and affects a slightly larger area than Botox and Xeomin. It has been reported that Dysport typically takes two to three days until the effects of the treatment are seen. Botox takes seven to ten days while Xeomin takes five to six days. Dysport may be the best option in areas where several injections are needed because of its easy spreading to cover a greater area on the face. In the areas where the spread needs to be minimized, Botox may be the best option to concentrate on deeper wrinkling. Over time with different Botox, Dysport and Xeomin injections, clients begin to favor which treatment works best for them.
By now, most clients who have undergone anti-aging treatments are familiar with Botox. However, with the emergence of Dysport and Xeomin clients have benefited with additional choices and competitive pricing. When initially deciding on which neurotoxin to inject or switch to consult with and choose a highly qualified medical professional. The best choice would be a plastic surgeon or highly experienced RN to conduct the injection. Botox, Dysport and Xeomin differ in administration technique and their skills are necessary to determine the proper dosage in order to achieve the best result.